Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Association of Medically Treated Depression and Age at Natural 44-year age range, several years before the median age. of menopause around age 50. If there is any link. between estrogen, depression, and menopause, Trisomy 21 and maternal age of menopause: does reproductive age Of the 35 women who were < 30 years of age (range:. 17-29 years of age) at time of delivery of a child with tri-. somy 21, 7 had experienced menopause. Drug trivora found in this post: normal age range for Drug List > Health Message Boards > trivora > normal age range for perimenopause normal age range for perimenopause (Menopause board) European Journal of Human Genetics - Nonlinear association between We present evidence for a nonlinear association between menopause age and premutation size suggesting that premutations in the mid-size range are at What is the age range for people starting menopause? What is the age range for people starting menopause? Menopause - Wikipedia, the free encyclopedia The average age of menopause is 51 years, and the normal age range for last period ever is somewhere between age 45 to 55. Age 55 to 60 for last period ever Menopause Age of Onset, Family History - Ask the Doctor - HealthTalk Will I hit menopause at roughly the same age my mother did? Can I expect similar symptoms? In general, what's the age range for menopause symptoms to start? Correlates of age at natural menopause: a community-based study in Numerous studies on the distribution of age at menopause have been . The age range of the women with NM (n = 289) was 30-59 years; the age range was Medical College of Wisconsin Patient Care (Patient Age Range: 12+) Women's Health, Obstetrics and Gynecological Services, Menopause Issues, Birth Control, Female Adolescent Health PII: 0020-7292(95)02354-F question the validity of this age range when ap-. especially in the non-Western countries. plied to non-Western societies. The age range of. the menopause From Dr. JoAnn Manson: The Age Range for Fertility So it's best to use a back-up contraceptive until you have gone through menopause for sure. The average age of menopause is 51, but that doesn't mean you Smoking's Effect on the Menopause Clock - Journal Watch Women's Health Smoking and early menopause are among the risk factors for osteoporosis and In a cross-sectional study of more than 2000 women (age range, 5961), Menopause Blood pressure (BP) is also known to increase more steeply around the age range during which women reach menopause 4. Whether this is related to menopause Relative Contributions of Years since Menopause, Age, and Weight with age and years since menopause (YSM) separately and The mean age of the postmenopausal women was 59.9. f 8.5 yr. (sD;. range, 32-80). The Menopause Web Reference The menopause is a normal and natural event in every woman's life. So the age range of women becoming menopausal is from teenagers to those who are 60+. Early Menopause - what is it and what causes it? What age is your definition of "early"? You are addressing an important issue and age range for menopause can be and ignorance of its wide variations. Health 24 - Menopause, Age and menopause The range for the age of natural menopause is approximately from age 48 to 55. Premature menopause: spontaneous menopause occurring before age 40. Menopause - Causes, Symptoms and Treatment for the Hormonal Premature menopause: The average age of US women in whom menopause occurs is 51 years. The most common age range at which women experience menopause is OBGYN.net Menopause, Perimenopause & Postmenopause: Definitions Although a menopause age of 57 and over is regularly reported, the age of the The median length of the perimenopause is 4 to 5 years (range: 1 - 9 yrs). |
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