Study Finds Menopause Symptoms Can Be Predicted

The number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.

Researchers now say they may be able to predict when that clock will wind down.

And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left.

According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason.

Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction.

"If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments."

Others reiterate, however, that the findings should be treated with caution.

"Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life."

According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000.

The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold.

The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause.

The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct.

While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated.

The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40.

SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction

melatonin and menopause
Menopause Message Boards and Menopause Forums -- Power Surge
Please send an email to admin@superhumanradio.com and request the study on melatonin and menopause. - Carl. Go to the top of the page. + Quote Post

Melatonin and menopause : Medications.com
menopause side effects associated with Melatonin. Share & Read Melatonin Menopause side effects & conditions. Post a new Melatonin side effect

Effects of Melatonin in Perimenopausal and Menopausal Women
MELATONIN AND MENOPAUSE. PATIENTS AND METHODS. Patients and Treatment. A formal and fully documented application for the conduction of the clinical trial

Melatonin May Raise Thyroid Hormone Levels in Perimenopausal and
(Effects of melatonin in perimenopausal and menopausal women: a randomized and placebo controlled study. Menopause Center, Madonna delle Grazie Health

Changes in nocturnal pineal melatonin synthesis during the
Melatonin and menopause. were mixed with. 50. pL of 4 mM serotonin and 50. pL of 2 mM acetyl CoA (or 50 pL of 40 pM. N-acetylserotonin and 50 pL of 20 pM

Soy + Melatonin: Slight Effect in Menopause
Soy and melatonin may offer some help to women with hot flashes, insomnia, and other menopausal symptoms. But not a lot.

Melatonin
One study evaluating the relationship between hormones, melatonin and menopause noted that menopausal women with the lowest levels of melatonin were able to

Menopause and Melatonin
Melatonin Canada. View all articles listed at Melatonin Canada. Menopause and Melatonin. Vaspressin, Vasotocin and Melatonin are Endogenous Antipyretics

The Way Up Bookstore: Hormone / Menopause / DHEA / Melatonin
BOOKSTORE CATEGORY: HORMONE/MENOPAUSE/DHEA/MELATONIN/GROWTH HORMONE: provide the foundation for this guide to reversing the effects of menopause.

Soy isoflavones, melatonin, not effective in relief of menopause
Soy isoflavones, melatonin, not effective in relief of menopause symptoms from Townsend Letter for Doctors and Patients in Health provided free by Find

Menopause
Melatonin and DHEA have become the dietary supplement fads du jour, and it is tempting to believe the hype that Changes that occur during menopause.

Endocrine regulation of the course of menopause by oral melatonin
show that melatonin administration was able to delay the characteristic endocrine changes that occur during the course of menopause.

Soy + Melatonin: Slight Effect In Menopause - News, Search Jobs
Soy + Melatonin: Slight Effect In Menopause 2/23/2004 Soy and melatonin may offer some help to women with hot flashes, insomnia, and other menopausal

Power Surge Forums > The Relationship Between Melatonin and Menopause
Please send an email to admin@superhumanradio.com and request the study on melatonin and menopause. - Carl. Duch. Oct 19 2006, 12:19 AM

All the info you need on how menopause can affect sleeping
Sleep Disturbances: Menopause and Melatonin We do not know why menopause causes a jump in more sleep disturbances and it may just be that hot flashes

Melatonin
Menopause. Melatonin supplements may benefit menopausal women by promoting and sustaining sleep. Peri- or postmenopausal women who use melatonin supplements

The Menopause Profile
High melatonin levels may bring about a lack of ovulation in women as well as decreased body temperature. Menopause Profile. The Menopause Profile measures

Effects of melatonin in perimenopausal and menopausal women: a
Menopause Center, Madonna delle Grazie Health Institute, Velletri, Rome, Italy. In aging humans, night levels of melatonin (MEL) decline progressively.

Melatonin
Melatonin - new wonder drug? The facts aren't all in and the jury's still out. Melatonin and Violent SleepMelatonin and Menopause Melatonin Mantra


melatonin and menopause
age does menopause start
boston in menopause play
homeopathy menopause
early symptoms of menopause