Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Women's Health Advisor 2005.4: Menopause Most women go through menopause between ages 45 and 55. muscle and joint pain; dry skin; palpitations (awareness of a fast or irregular heartbeat) Menopause help, pain relief, Australia, hot flushes relief, joint Zen Therapeutics herbal tinctures, relieving pain, improving blood circulation, reducing inflammation, promoting repair. - Harmony Tincture, a womens Menopause and Joint Pain, Treatment discover the causes and treatment for joint pain during menopause. Osteoarthritis, Joint Pain & Arthritis Relief Information Center Menopause Symptoms and Menopause Treatments Resource Center RealAge's Menopause Osteoarthritis, Joint Pain, and Arthritis Relief Center Visit RealAge's Joint pain and estrogen deprivation Women treated with aromatase inhibitors often experience joint pain and suppression of estrogen and studies of natural menopause, the authors offer a Menopause Message Boards and Menopause Forums -- Power Surge Joint Aches and Pain / Arthritis. Forum Options V . Living With Mental & Physical Health Disorders Plus Menopause! |-- Insomnia / Sleep Disorders / Access Health And Wealth: menopause joint pain Excerpt - page 22: " more related to aging than menopause. These changes include weight gain, heart palpitations, joint pain, headache, and changes in Menopause Symptoms Joint Pain | Menopause This article shows how the menopause is related to the joint pain. Muscle and joint pain can't take estrogen - Menopause - MedHelp Muscle and joint pain can't take estrogen. Answered by. Machelle Seibel, MD - Women's Health, Menopause, ReproductiveMedicine Your new Le Club Discussion Groups: menopause - joint pain #2720 - 06/23/04 08:10 PM menopause - joint pain - numbness - etc #2721 - 06/24/04 08:18 AM Re: menopause - joint pain - numbness - etc Menopause and joint pain â“ are they connected? Many women wonder if menopause and joint pain are connected. Studies have shown that postmenopausal women experience some sort of joint pain. Menopause (Joint Pain) - Factors Associated with Joint Pain among NewsRx is the leading source of news and information on Menopause (Joint Pain) Estrogen Deprivation and Joint Pain Estrogen Deprivation and Joint Pain September 2, 2005 as well as natural menopause, cause arthralgias or joint pain and musculoskeletal aching. Joint Protect - Bone Joint Pain | Joint Pain Rash | Joint Joint Protect is the most powerful Natural Joint Relief Alternative to anti-inflammatory drugs ever Joint Protect, Bone Joint Pain, Joint Menopause Pain National Association of Baby Boomer Women - NABBW - Empowering One of the reported problems of menopause is joint pain. Joint pains are usually associated with osteoporosis and arthritis, which results in weakening of MENOPAUSE SYMPTOMS: DRY EYES AND JOINT PAIN Some lesser known symptoms of the menopause are dry eyes and joint pains. Joint pain and muscle stiffness â” a natural approach Almost all women in perimenopause and menopause suffer from joint pain or stiffness. Learn about the causes of joint and muscle pain and how to find relief Aching joints, Muscle aches - Alternative remedies The Menopause Self Help Book by Susan M. Lark, M.D., Joint pain can begin before menopausal years and become more troublesome during these years. |
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