Study Finds Menopause Symptoms Can Be Predicted

The number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.

Researchers now say they may be able to predict when that clock will wind down.

And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left.

According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason.

Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction.

"If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments."

Others reiterate, however, that the findings should be treated with caution.

"Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life."

According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000.

The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold.

The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause.

The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct.

While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated.

The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40.

SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction

itching menopause related vaginal
Vitamin E for Hot Flashes (and Vaginal Thinning and Itching
Vitamin E for Hot Flashes (and Vaginal Thinning and Itching) - Menopause is a personally written site at Related Links:. Dizziness, Fatigue, Hair Loss

Symptoms, Their Causes & Cures Vaginal Itching
If you're approaching menopause, ask your doctor about treatments for itching caused by changes that are taking place in the vagina.

Symptoms: Symptoms and Diagnosis of Gynecologic Disorders: Merck
Hormonal changes at menopause can cause vaginal dryness, which leads to itching. Skin disorders such as psoriasis or lichen sclerosus can cause itching.

Itching and Menopause are Often Related
Vaginal Itching and Menopause Menopause has been known to cause vaginal dryness, which in turn can become More Itching And Menopause Related Articles:

Menopause Symptoms: Vaginal Dryness
Menopause itching due to dryness can also become painful and annoying. Incontinence also often occurs with vaginal dryness. As estrogen levels decrease,

Vaginal Dryness & Itching Treatment - Post Menopause Treatment
Vaginal Dryness and Itching Treatment. Dry and itching anything is annoying and crazy making. So you will likely want to get on this menopause symptom

menopause,constant genital itch. - Menopause - MedHelp
This is a discussion on MedHelp about menopause,constant genital itch. Vaginal discharge atrophy and my itchBiliopancreatic diversion with duodenal

itching - Menopause - MedHelp
Menopause. - Ask A Question. Related Forums Related Forums. Medical Communties Vaginal itching is one of the symptoms of menopause.

Menopause Message Boards and Menopause Forums -- Power Surge
I have bouts of intense vaginal itching, usually at night or early in the . Depression (Menopause Related) / Anti-depressants / The Blues / Sadness

Candida Diet
Vaginal pain, itching or dryness can soon drive you to despair, . Other supplements that can help with menopause-related vaginal dryness are the B

Atrophic Vaginitis (Vaginal Dryness) - Patient UK
After the menopause many women develop a dry vagina, and other symptoms Itch. The skin around the vulva is more sensitive and more likely to itch.

MedlinePlus Medical Encyclopedia: Vaginal itching
Vaginal itching is a tingling or uneasy irritation of the skin of the vagina For itching related to menopause, your doctor may consider estrogen cream

Vaginal dryness - CNN.com
An estimated 10 percent to 40 percent of women who've reached menopause have signs and symptoms related to vaginal dryness.

MENOPAUSE: Common Problems and Their Remedies
Burning and itching sensations may signal vaginal dryness which can be Women who have experienced breast tenderness related to their menstrual cycle are

Vaginitis - CNN.com
Vaginal itching and burning also can result from vaginal dryness caused by a drop in your hormone levels after menopause or surgical removal of your ovaries

Genital itching - WrongDiagnosis.com
The estrogen withdrawal in menopause causes atrophic vaginitis (thinning and dryness of the Vaginal candidiasis Vaginal itching, Vaginal irritation

Vaginal itching - WrongDiagnosis.com
Read the full text of published book sections related to Vaginal itching from the following published medical books for Menopause vaginal irritation


itching menopause related vaginal
intercourse after menopause
menopause breast size
diagnosis menopause
hair thinning menopause