Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Treatment of Non-Infectious, Non-Atrophic Vaginitis (Vaginal Treatment of vaginitis, treatment of vaginal irritation, treatment of irritation of the or petroleum jelly to your vulva and the inside of your vagina. Irritant effect of a model surfactant on the human vulva and Irritant effect of a model surfactant on the human vulva and forearm. studied in two groups of 20 healthy women each, 10 before and 10 after menopause. Vaginal Pain During Menopause: Why Estrogen Deficiency May Not Be With complications ranging from mild irritation to significant pain, Menopause is commonly associated with vulvar pain, leading to impaired sexual OBGYN.net Publications "Gynecologic Causes of Pain - Internal: In Vulvar pain, or vulvodynia, can have many origins. Most common are temporary irritation from yeast or other vaginal infections. If vulvar pain or irritation Pain at Midlife Vulvodynia is defined as chronic vulvar discomfort with symptoms including burning, stinging, irritation, and rawness. Ninety-five percent of the time Compositions and methods of treating irritation and kit therefor In fact, the infections may extend to and involve the external vulvar and in the perineum), douching, sexual relations, menopause, tight clothing, Women's Health Advisor 2005.4: Vulvar Dystrophy It happens mostly during puberty and menopause, but it can occur at any age. The cause of vulvar dystrophy is often not known. Sometimes irritation of Vaginal Dryness and Menopause As a woman approaches menopause, the levels of estrogen in the tissues of the vulva and the lining of the vagina diminish. This causes a condition known as WikiAnswers - Can swelling of the vulva be caused by irritation From breast cancer to menopause, the health conditions every woman should swelling of the vulva be caused by irritation from rubbing against clothing? Vulvitis - Itching - Red - Swelling - Blisters - Vulvar As hormone levels drop during menopause, vulvar tissues become thinner, drier, not to scratch as this can lead to further irritation and/or infection. Vaginal Dryness - Causes and treatments | Menopause Lifestyle Vaginal dryness and irritation are common symptoms of menopause which affect This has a direct effect on the tissues of the vulva and vagina and Postgraduate Medicine: Women's Healthcare Symposium: Vulvar Preview: Like many other parts of the body, the vulva is affected by sessation of estrogen after menopause. Vulvar pruritus and irritation are common Tips for Chronic Vulvar Pain Management - G01 Once a woman has vulvar irritation she should avoid putting any products on the This is especially true after the menopause when more natural dryness Menopause and the skin. DermNet NZ Menopause and the skin. Authoritative facts about the skin from the New Chronic vulvar burning, irritation, stinging and rawness (rather than itch) AGS Aging in the Know Common disorders include irritation, inflammation, and infection. Tumors of the vulva are fairly rare but do develop in some postmenopausal women. eMedicine - Vulvovaginitis : Article by Omnia M Samra, MD A survey by the North American Menopause Society indicated that up to 10% of . The vulvar skin is susceptible to irritation and is easily traumatized by Curing Vaginal Infections: Best Ways to Fend Off Infections Atrophy occurs normally after menopause due to a fall in hormone . Whatever you do, if vulvar irritation or itching fails to go away be sure to check Vulva Irritation Keywords: vagina vaginal discharge vulva vulvar itch itching sensitivity estrogen hormone menopause estradiol oestradiol side effects complications rash Vulvar Dermatoses â“ Irritant and Allergic Contact Dermatitis of gradually develop and increase in depth until menopause when involution begins. Far more frequent than acute vulvar irritant dermatitis is chronic |
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