Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Menopause Perimenopause Mature Sexuality Aging HRT Womens Health perimenopause, what you can expect, and what this period of transition can as irregular and sometimes heavy menstrual periods during the perimenopause. Menopause and Perimenopause - Yahoo! Health If you have irregular bleeding during perimenopause or you are taking continuous .. reduce heavy, irregular menstrual periods during perimenopause. Menstrual irregularities - WrongDiagnosis.com Vaginal bleeding; Perimenopause Spotting, abnormal menstrual bleeding, irregular periods, irregular periods, change in premenstrual symptoms, What can I do about irregular bleeding during perimenopause What can I do about irregular bleeding during perimenopause? from Harvard Womens Health Watch in Health provided by Find Articles. OBGYN.net Menopause & Perimenopause Ask The Expert March, 2000 Q: Change in sleep patterns, irregular periods, are these symptoms of perimenopause?I am a 43 year old. Last spring, I skipped 3 periods. Irregular Menstrual Periods in Perimenopause and Menopause Irregular periods are a common symptom of perimenopause, the time before Many women see similarities between their menstrual cycles during their forties Irregular periods - understanding the menstrual cycle Women entering perimenopause often have irregular periods due to an imbalance of Click here to learn more about irregular periods in perimenopause. Irregular periods in perimenopause "Irregular" periods as feature of perimenopause .. During this time I had two light periods (I *guess* they were periods!) but my norm seemd to be floods Answer to a newbie's questions on perimenopause 'Irregular' periods can mean anything from more frequent to less often with . Most of the physical signs that occur during peri tend to be transient, Perimenopausal and menopausal bleeding What happens to periods during menopause? Why is bleeding irregular in perimenopause? Regular periods are the result of a precise hormone balance Perimenopause - CNN.com During perimenopause, sexual arousal and desire may change. Irregular periods are a hallmark of perimenopause. Most of the time, this is normal and Is Heavy, Irregular Bleeding, or Bleeding After Sex Normal During A. While it's normal to experience irregular bleeding during perimenopause, it's important to understand that not all menstrual problems are caused by Bleeding Between Periods spotting metrorrhagia causes treatments Are you experiencing irregular bleeding or spotting between periods? the amount of blood lost during your period is only about two to eight tablespoons. Menopausal Bleeding - Irregular Bleeding During Perimenopause and Irregular Menstruation During Perimenopause. Irregular bleeding is very common in women Often, the easiest way to treat irregular periods is with low The menopause Many women experience symptoms of the menopause and irregular periods for .. What you can do before, during and after a night out to ease symptoms. Womens HealthCare Forum: Menopause Midlife is often considered a period of increased risk for depression in women. The drop in estrogen levels during perimenopause and menopause can lead to Menopause Symptoms and Relief The clearest signs of the start of menopause are irregular periods (when periods come Eat cereal and milk products at bedtime or during the night. Symptoms Of Menopause - Irregular Bleeding In general, irregular periods are very common during the perimenopause. The most common early menstrual irregularity noticed in the perimenopause is a Healthy Viewpoints Abnormal Uterine Bleeding During Perimenopause. By Susan J. Momont, MD, FACOG see your healthcare provider if you are experiencing irregular bleeding. |
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