Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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NewsRx Search Results on International Menopause Society World's Largest Source of Health Information. Health, Medical, Biotech, Legal, Business & Clinical Research News for Professionals and Knowledgeable ISGE - Curriculum Vitae 2001- International Menopause Society, Executive board 2005 International Menopause Society, Scientific Program Chairman for 11th World Congress IMS reaction to report on breast cancer incidence in 2003 in US While being pleased with these new data on the incidence of breast cancer, the International Menopause Society (IMS) advises caution in linking these two International Congress Series : Menopause-related definitions First international menopause society definitions 1976 . W.H. Utian, The International Menopause Society menopause-related terminology definitions. International Menopause Society - EU Obstetrics & Gynecology 2007 International Menopause Society - EU Obstetrics & Gynecology 2007 - Issue II, join our in our global Touch Briefings directory and share your news, NeLM - International Menopause Society calls for change to HRT The International Menopause Society has issued a plea to health authorities to change their current recommendations, which they say are based on â˜wrongly Updated Recommendations On Postmenopausal Hormone Therapy From This was the atmosphere in which the International Menopause Society (IMS) initiated the IMS Workshop held in Vienna (December 2003) and the IMS Position International Menopause Society - Educational Materials Free International Menopause Society - Educational Materials Free Online Text books Free Online books interview questions articles buy books medical business IngentaConnect The view of The International Menopause Society on The view of The International Menopause Society on the Women's Health Initiative. Author: Schneider H.P.G.1. Source: Climacteric, Volume 5, Number 3, EMAS: European Menopause and Andropause Society EMAS is recognised by the Swiss Government and acknowledged by the International Menopause Society as the official Regional European Menopause Society. Statement from The International Menopause Society The International Menopause Society (IMS) is profoundly concerned that the European Medicines Evaluation Agency (EMEA) has ignored important information in Menopause International Members of the British Menopause Society receive the journal free of charge. Click the link above for more information. Menopause International is a highly International Menopause Society - Home A non-profit organization focused on promoting knowledge concerning climacteric and menopause. Provides information on facts regarding hormonal treatment, Taylor & Francis Journals: Welcome The Journal of the International Menopause Society Visit the organisation site. Published By: Informa Healthcare. Volume Number: 11 International Menopause Society reaction to report on breast cancer A special report in the April 19 issue of the New England Journal of Medicine 1 brings initial analysis of data from the National Cancer Institute's Welcome to the Australasian Menopause Society Press Release International Menopause Society - NEJM Special Report on Breast Cancer Issued on behalf of the International Menopause Society by The International Menopause Society Calls Upon Health Authorities As opinion leaders in the field of menopause medicine from various areas in the world, we wish to emphasize the following points concerning postmenopausal |
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