Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Ask An Expert Surgically Induced Menopause And Fibromyalgia - AOL Body Is there any connection between surgically induced menopause and fibromyalgia? And does taking estrogen seem to help or hurt the condition? HON Mother & Child Glossary, Gynaecologic Problems: Menopausal The term surgical menopause refers to induced menopause caused by surgical removal Bilateral oophorectomy is the most common cause of induced menopause. VCD-Induced Model of Menopause - The Jackson Laboratory JAXá® Services in Bar Harbor offers the VCD-induced menopause model on at least 5 genetic backgrounds: C57BL/6J (000664), an atherosclerosis-susceptible Does a woman with surgically induced menopause, on oestrogen only Initial question: A 51- year old patient had a surgically induced menopause (TAH and BSO) in her 30s and has been on oestrogen only HRT ever since. All About Bleeding : Hot flashes worse after surgery-induced menopause Hot flashes worse after surgery-induced menopause. Last Updated: 2006-05-23 14:21:02 -0400 (Reuters Health). NEW YORK (Reuters Health) - Women who undergo WikiAnswers - What is chemically induced menopause Answer "What is chemically induced menopause?" Even if you can't offer a complete answer, help us get things started. Premature and Induced Menopause - Yahoo! Health There are certain situations that bring about menopause earlier than usual. About one percent of women cease menstruating before age 40. Menopause Women going through induced menopause may have more severe menopausal symptoms, and are usually treated with hormone therapy. Surgical Menopause, Induced Menopause - WebMD Not all women undergo natural menopause. Some women experience induced menopause as a result of surgery or medical treatments. Chemo-induced menopause: from hot flashes to life changes - The For premenopausal women who are diagnosed with cancer, chemo-induced menopause comes quickly, without warning. There are no years of perimenopause, Sexual Desire After Hysterectomy Estrogen alone may be enough to restore libido, but some women have dramatic results with testosterone. Hysterectomy Induced Menopause - Women's Health Zone Women who have a hysterectomy, but have their ovaries left in place, will not have induced menopause because their ovaries will continue to make hormones. Medically Induced Menopause Medically induced menopause doesn't offer a women the chance to enter menopause gradually. While physicians conducting hysterectomies no longer routinely surgical menopause, early menopause, medical menopause - Women The term Áœinduced menopauseÁ« describes menopause caused by a medical intervention. The most common cause of induced menopause is the surgical removal of Menopause, induced definition - Menopause: Menopausal Health and Menopause, induced: Induced menopause occurs when menopause is due to an unusual ("unnatural") event. It is induced when the ovaries are surgically removed The advantages and disadvantages of natural and surgically-induced "Have there been any studies comparing a "natural" menopause to a surgically-induced menopause? Has there been any medical consensus that one is more Induced menopause definition - Menopause: Menopausal Health and Induced menopause: Menopause may be due to an unusual ("unnatural") event. It is induced when the ovaries are surgically removed (by bilateral oophorectomy) Ovacome : Treatment-induced menopause The fact that with an early induced menopause the woman has a prolonged period without the natural benefits of oestrogen, she may wish to give particular |
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