Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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What is the effect of HRT on fibroids? : NLH Question Answering Fibroids will usually shrink to about half their original size after menopause. A review of the literature found 5 randomized controlled trials looking at Uterine Fibroids Disrupt Life, Fertility Often their size diminishes after menopause. "Often uterine fibroids don't of women with fibroids miscarry, particularly when the fibroids increase or UCSF Women's Health - Comprehensive Fibroid Center During pregnancy, when the hormone levels are high, fibroids tend to increase in size. After menopause, when the hormone levels are low, fibroids stop Fibroid Tumors of the Uterus This is thought to occur because of the increase in estrogen levels during Fibroids typically improve after menopause when the level of estrogen Uterine Fibroids Symptoms, Diagnosis and Treatment - SIR Fibroids can dramatically increase in size during pregnancy. They typically improve after menopause when the level of estrogen, the female hormone that Uterine Fibroid Tumors or Tumor Postmenopausal women usually are not considered for UFE, since fibroid symptoms tend to lessen or go away after menopause. Recent studies have shown, Case Discussions and Analysis Four - Menopause, Menopause after Hope For Fibroids-Case Analysis Four - Menopause cases, 62 and 65 years old, menopausal bleeding, fibroids growing after menopause, endometrial biopsy, Hope For Fibroids FAQs 3-3 Uterine Fibroids Recovery HRT, Hormone "Fibroids after the menopause are not generally found to be sensitive to HRT The final outcome from this study was HRT does increase uterine fibroid Uterine Fibroids After menopause, no new uterine fibroids are likely to develop, linked to estrogen level - uterine fibroids may increase in size during pregnancy or Uterine fibroids - Wikipedia, the free encyclopedia As estrogen levels decline with menopause, fibroids tend to regress after menopause. Hormonal therapy is based on these facts. MTV Super Select Buenas dias - night sweats sweating - losing weight after menopause - herbal cure night sweats - infant night sweats - increase fibroids after menopause Uterine fibroids guide - MayoClinic.com He explained that the reproductive hormones, estrogen and progesterone, likely fuel fibroid growth. After menopause, ovaries stop producing these hormones, About Uterine Fibroids Using birth control pills does not appear to increase risk, except very rarely. Hormone therapy after menopause usually does not make fibroids grow. MedlinePlus Medical Encyclopedia: Uterine fibroids These usually take place after menopause. The most common warning sign is rapid growing of a fibroid. A definite diagnosis is usually not made until the Fibroids and estrogen replacement therapy - H01 Fibroids decrease in size to a very small size after menopause if a woman does not take estrogen replacement. They do not totally go away; there is always a Disease Profile Fibroids - Uterine Leiomyomata - G01 Most of these tumors are asymptomatic except when they increase in size, After menopause, the fibroids and entire uterus get smaller unless hormone Maturitas : Differences between the pre-menopausal and post Reduction in cell size within fibroids has also been reported after the menopause 11 and 12, making it difficult to explain the relative increase in MTV Super Select Aloha - increase fibroids after menopause - night sweats tyroid medicine - menopause syptoms - diabetes night sweats - menopause and sarafem - menopause and Help for Women with Uterine Fibroids - Menopause - Susun Weed Fibroids increase in size during pregnancy, when progesterone production is high, and atrophy after menopause, when progesterone levels decrease. |
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