Study Finds Menopause Symptoms Can Be Predicted

The number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.

Researchers now say they may be able to predict when that clock will wind down.

And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left.

According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason.

Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction.

"If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments."

Others reiterate, however, that the findings should be treated with caution.

"Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life."

According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000.

The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold.

The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause.

The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct.

While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated.

The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40.

SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction

hypothyroid and menopause
Hypothyroidism Discussions at DailyStrength: menopause and
Its hard to tell what symptoms are menopause and which are thyroid problems. Are there any books out there on that specific situation?

Health Concerns - Thyroid
Symptoms for both hypothyroidism and menopause commonly occur and include depressed mood, decreased energy and decreased memory.

ADHD/ Hypothyroid/menopause, Learn about ADHD/ Hypothyroid
Learn about ADHD/ Hypothyroid/menopause at UnitedProject.

ADHD/Hypothyroidism/menopause
I am an adult suffering from ADHD, Hypothyriodism, menopause, I need help in my every day life and h.

Perimenopause - Menopause hypothyroidism information for weight loss
Women's Menopause Health Center October 15, 2005 Newsletter. More on Perimenopause - Menopause Hypothyroidism. Did you know that hypothyroidism is more

Best Hypothyroidism Treatment -May Cause Early Menopause
Hypothyroidism May Cause Early Menopause Menopause can be a difficult time for many women. Reductions in circulating estrogen hormone levels result in a

Hypothyroid, menopause and hormones.
I have had hypothyroidism for years.take natural thyroidmade it through menopause.Like all ladies over 50 I have found the fat loss battle is with

The Menopause Diet - Hypothyroidism and Soy
Obviously, they forgot about women in these studies, especially those of us in menopause or affected by hypothyroidism. As described in The Menopause Diet,

Menopause and Hypothyroidism
Menopause and hypothyroidism have common symptoms, such as depressed mood, decreased energy and decreased memory, among others. Often these symptoms are

International Journal of Gynecology & Obstetrics : Screening for
According to the diagnostic tests, one-quarter of the women attending our menopause clinic had secondary or tertiary hypothyroidism.

POF and Hypothyroidism - Menopause - MedHelp
POF and Hypothyroidism. Answered by. Machelle Seibel, MD - Women's Health, Menopause, ReproductiveMedicine. University of Massachusetts Medical School MA

Mary Shomon Radio Interview Re: Larrian Gillespie's The Menopause
Read my Interview with Larrian Gillespie, M.D. on Menopause, Weight Loss and Hypothyroidism now. In this interview, popular author Larrian Gillespie,

IngentaConnect Screening for hypothyroidism at a menopause clinic
Screening for hypothyroidism at a menopause clinic. Authors: Suchartwatnachai C.1; Thepppisai U.; Jirapinyo M. Source: International Journal of Gynecology

Hypothyroid and possible menopause-whatta mess ;) - Menopause
This is a discussion on MedHelp about Hypothyroid and possible menopause-whatta mess ;). Community members of MedHelp provide help, support, guidance and

Learn about hypothyroidism and low thyroid function in women
Hypothyroidism and hormonal imbalance. Over 20% of women in menopause are diagnosed with thyroid dysfunction, principally hypothyroidism, and millions more

The Thyroid/Menopause Connection
Drs. Richard and Karilee Shames on the connection between hypothyroidism and underactive thyroid problems and menopause, from Mary Shomon, Thyroid Guide,

The Thyroid/Menopause Connection -- Information from Richard and
This underlying problem is commonly coexistent hypothyroidism. Not only does low thyroid become more common as women mature, but in addition, menopause and

Thyroid Disease and Menopause / Thyroid Disease Information Source
Hormone replacement therapy may be indicated now, even if menopause symptoms are gone. For women with hypothyroidism, it's important to remember one thing

Hypothyroidism in menopause, thyroid hormone imbalance, and
Find information on hypothyroidism in menopause, thyroid hormone imbalance, hypothyroid symptoms, and natural hypothyroidism treatment options.


hypothyroid and menopause
menopause body odor
hormone menopause
kathy menopause moving smith through
flash hot menopause night sweats