Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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What are Hot Flashes? This reduction in supply can temporarily confuse the hypothalamus, causing a significant rise in body temperature and very uncomfortable hot flashes. Menopause - Fulltext: Volume 11(4) July/August 2004 p 369-371 2 The thermoregulatory center in the hypothalamus activates these mechanisms Hot flashes resulting from a chemically-induced menopause can be of a more Dealing With Hot Flashes -- ThirdAge Hot flashes, the most common symptom of menopause, may be preceded or To be more precise, it alters the hypothalamus, a part of your brain that acts All About Hot Flashes Hot flashes are mostly caused by the hormonal changes of menopause, A diminished level of estrogen has a direct effect on the hypothalamus, Hot Flashes Caused By Menopause Article The drop in estrogen confuses the hypothalamus so it raises the body temperature to read "too hot," and hot flashes caused by menopause result. Hot Flashes | myLifetime.com Hot flashes commonly occur in women around the time of menopause. In a hot flash, the hypothalamus seems to sense that your body is too hot even when it U.S. Food and Drug Administration Attitudes Towards Menopause During menopause, as the ovaries produce less estrogen, the hypothalamus senses and How many women are affected by hot flashes has not been clearly Hot Flashes - Women Living Naturally Hot flashes are often one of the first indications that menopause is approaching. The brain center that secretes these hormones, the hypothalamus, hot flushes, hot flashes, night sweats, menopause - Women Living Hot flashes are caused by the hormonal changes of menopause. A diminished level of estrogen has a direct effect on the hypothalamus, the part of the brain What is a Hot Flash? The hypothalamus is responsible for the control of your sleep cycles, sex hormones, appetite, At least 85% of women get hot flashes during menopause. Survivor's Guide to Surgical Menopause: Hot flashes While the mechanism of this is not fully understood, it looks as though a hot flash results from a delusion on the part of the hypothalamus (a portion of Discovery Health :: Menopause :: Menopause printer friendly version. Menopause. No one is really sure what causes a hot flash, but the lessened estrogen makes the hypothalamus go out of control. Menopause Hot Flashes | Menopause Hot Flash The hypothalamus utilizes blood flow as a means to help regulate Hot flashes and panic attacks are some of the most common menopause symptoms. Menopause hot flashes and heart rate Learning about menopause hot flashes and heart rate will help women treat it the main reason for this is that the hypothalamus (the heat regulatory area Excessive sweating by menopause hot flashes Excessive sweating by menopause hot flashes can worsen and spoil your life the main reason for this is that the hypothalamus (the heat regulatory area Menopause and Hot Flashes Fevers and hot flashes both are thought to originate in the hypothalamus (a part as in natural menopause - hot flashes, vaginal mucosal atrophy (which, Menopause Symptoms..hot flashes, night sweats, itching Hot flashes, flushes, night sweats and/or cold flashes, clammy feeling During menopause, as the ovaries produce less estrogen, the hypothalamus senses InteliHealth: In a hot flash, the hypothalamus seems to sense that your body is too hot In most women who undergo natural menopause, hot flashes subside within 2 to New Attitudes Towards Menopause During menopause, as the ovaries produce less estrogen, the hypothalamus About 10 percent of the women who continue to have hot flashes still have them |
| hypothalamus and menopause hot flashes |
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