Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Could my chronic hives be related to a hormone imbalance I've been blaming all my other faults on menopause (out of 35 symptons I've got 36)and would like to blame it for my hivesHives The Hives Menopause Connection Learn about the hives menopause connection. A look at the link between hives and hormones. The causes of hives, prevention, and treatment options. Cure For Hives If you are worried about hives on face, hives at night or the hives menopause connection, please be sure to follow the links to those sections. The Mysterious Hives of Menopause The hives of menopause are a mystery to medical science, which has yet to provide an explanation for their appearance. Yet the hives of menopause seem to be WikiAnswers - Do hives or transient skin rashes accompany menopause In some women (some may never have had an allergy) until menopause will have more allergies. I never had any allergies and when I went into menopause I got Menopause and Hives Learn about Menopause and Hives, and search for other issues and information about coping with modern menopause. Hives and Menopause - Menopausal Hives and How to Relieve Them Hives and Menopause. Hives, medically know as urticaria, are red, raised, blotchy lesions on the skin that itch like crazy. Hives can affect Chronic Hives If the hives last for more than 6 weeks, it is called chronic urticaria. hormonal changes - since you are going through menopause - and will end soon. WOMENS-HEALTH Messages for November, 2002: Re: Menopause and Hives >are the hives due to hormonal levels dropping as I progress through >perimenopause to menopause? My family doctor says no they are due to WOMENS-HEALTH Messages for November, 2002: Menopause and Hives My question to you is are the hives due to hormonal levels dropping as I progress through perimenopause to menopause? My family doctor says no they are due |
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