Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Abnormal Uterine Bleeding - Menopause Abnormal Uterine Bleeding - Menopause is a personally written site at BellaOnline. Excessive bleeding can be annoying, distressful, and expensive. Menopause symptoms, diagnosis, and treatment on MedicineNet.com Menopause symptoms include hot flashes, abnormal vaginal bleeding, bleeding during perimenopause whereas others have unpredictable, excessive bleeding. WikiAnswers - Does excessive bleeding due to menopause affects a Answer "Does excessive bleeding due to menopause affects a lady already diabetic?" Even if you can't offer a complete answer, help us get things started. Heavy Bleeding -- what causes it and how to treat it Excessive menstrual bleeding affects one in five women. This leaflet describes some of the problems Rare, but more common in women after the menopause. Irregular periods - understanding the menstrual cycle We explain this in more detail in our article on post-menopausal bleeding. By the way, it is a myth that a woman goes into menopause because her body runs prolonged menstral bleeding perimenopause >> Medical Questions It is true that your prolonged and excessive bleeding is a result of an abnormal physiologic . Are symptoms in perimenopause the same as in menopause? long menstral period excessive bleeding >> Medical Questions I am 47 and entering my menopause. The problem is that I am experiencing heavy and excessive bleeding and have very long menstral period. Menopause Online This loss of estrogen causes the typical symptoms of menopause. Hysterectomy was often performed in the past to treat excessive bleeding. The menopause Mirena is currently the most effective non-surgical way of dealing with excessive vaginal bleeding. There are other drug options that can be used by Dysfunctional uterine bleeding During the years preceeding the menopause, changes in hormone levels The quality of life of women suffering from excessive bleeding is impaired in many Abnormal Uterine Bleeding - October 1, 1999 - American Academy of Menorrhagia, Prolonged or excessive bleeding at regular intervals . As women approach menopause, cycles shorten and often become intermittently Menstrual Irregularities, Heavy Bleeding, Spotting - Alternative You will become able to distinguish the normal "abnormalities" of menopause from really unnatural bleeding that needs attention and treatment. UpToDate Patient information: Abnormal uterine bleeding Bleeding that occurs between menstrual periods or excessive bleeding that occurs during Causes of abnormal bleeding during menopause include: excessive bleeding - Menopause - MedHelp excessive bleeding. Answered by. Machelle Seibel, MD - Women's Health, Menopause, ReproductiveMedicine. University of Massachusetts Medical School MA menop However, rarely is a hysterectomy the only choice when the problem is excessive bleeding. Donâ™t forget the value of a second opinion when procedures or Perimenopausal and menopausal bleeding Unless the bleeding is excessive, or a woman it at high risk for uterine How is abnormal uterine bleeding in menopause or perimenopause evaluated? Heavy uterine bleeding Iron deficiency anemia may result from excessive menstrual blood loss. It may also have other causes - slow bleeding elsewhere in the body esp. the GI tract Menopause and Heavy Bleeding Dysfunctional Uterine Bleeding (DUB) refers to excessive bleeding that is not related to fibroids, polyps, endometriosis, adenomyosis, pregnancy, Abnormal Uterine Bleeding / When Your Period is Too Heavy Another common cause of abnormal uterine bleeding is fibroid tumors. Other causes of excessive bleeding that your clinician should consider include: |
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