Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Effect of surgical menopause and estrogen replacement on cytokine Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells. R Pacifici, C Brown, E Puscheck, E Friedrich, JSTOR: Effect of Surgical Menopause and Estrogen Replacement on Those results prompted the current study, which was designed to investigate the effects of surgically induced menopause and subsequent estrogen replacement Hormone Replacement and Osteoporosis Medical Information Hormone replacement therapy (HRT) and estrogen replacement therapy (ERT) were initially indicated for treatment of the symptoms of menopause, Is Hormone Replacement Therapy Really Treats Menopause Symptoms In cases where if you prefer taking Hormone Replacement Therapy after menopause, then usually you will be prescribed only an estrogen replacement therapy Hormone therapy, treatment for menopause on MedicineNet.com Lack of estrogen after menopause adds another strain on the bones in addition to Most Women Unaware of Hormone Replacement Study · Surgery Best Bet for Menopause - Fulltext: Volume 8(1) January 2001 p 70-75 Hormone All eight patients received estradiol as estrogen replacement therapy in .. Hormone replacement therapy and survival after surgery for ovarian cancer. ScienceDirect - The American Journal of Surgery : Hormone Years of clinical wisdom, bolstered by consistent observational studies, have held that replacement of estrogen after menopause would restore the relative Estrogen Replacement Therapy and Anti Depressants - Menopause Tags: estrogen, hormone, menopause, Hormone replacement therapy, Depression, Roux-en-y stomach surgery for weight loss · Weight gain - unintentional Mayo Clinic - Mayo Clinic Research Shows Estrogen Protects Women's To protect against these conditions, estrogen replacement therapy may be warranted for women who had their ovaries removed before menopause. Menopause | IronOnline Health and Fitness Database According to Project Aware, "Perimenopause is the phase before menopause actually Many researchers and doctors believe estrogen replacement therapy is Menopause, Hormone Replacement and the Ovary Thankfully, estrogen replacement in the form of tablets, patches, How To Get Bigger Breasts Without Resorting To Pricey, Risky Implant Surgery HRT, Hormone Replacement Therapy Hormone Replacement Therapy for Menopause. What is hormone replacement therapy After menopause, there is much less estrogen and testosterone in the body Hormone replacement therapy, Information about Hormone replacement Hormone (or estrogen) replacement therapy is intended to improve and/or . If surgery is performed prior to menopause and the ovaries are removed, Hormone Replacement Therapy, Menopause Stock Image Search Results Hormone Replacement Therapy, Menopause,Medical Illustration database of the Total Hip Joint Replacement Surgery. May be customized by editing labels, Risk Management: Surgical Menopause It isn't entirely clear what effect estrogen replacement therapy (ERT) or . facing hysterectomy or gynecologic surgery. North American Menopause Society Menopause, Natural Hormone Replacement Therapy, Administering Menopause. Hormone Replacement Therapy (HRT). Natural Hormone Replacement Therapy. Administering Natural Hormone Therapy. A comprehensive treatment of Menopause: Hormone Replacement Therapy Hormone replacement therapy, or HRT for short, is a highly popular medical regimen used to help reduce the symptoms of menopause. eMedicine - Menopause : Article by Diana Curran, MD, FACOG Menopause - Menopause is a universal and irreversible part of the overall aging Resnick SM, Metter EJ, Zonderman AB: Estrogen replacement therapy and Life after gynecologic cancers: Surgical or premature menopause It's the same with a 'fast-forwarding' of menopause due to surgery or One concern is that the long-term effects of estrogen replacement are not really |
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