Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Delayed premature menopause following chemotherapy for early stage Methods: We evaluated the age of menopause in women with early stage breast cancer who remained premenopausal using data from the International Breast Science Links Japan | Bone Metabolic Imbalance Occurs at an Early Bone Metabolic Imbalance Occurs at an Early Stage of Natural Menopause Title;Bone Metabolic Imbalance Occurs at an Early Stage of Natural Menopause Women's health - For every stage of life Everything you need to know about managing you menopause transition. If ovarian cancer is diagnosed in the very early stages chances of survival are Menopause - Abstract: Volume 14(6) November/December 2007 p 995 Memory impairments with adjuvant anastrozole versus tamoxifen in women with early-stage breast cancer. Articles. Menopause. 14(6):995-998, November/December 10th World Congress on the Menopause, 2002 Dr. Sherman presented this new staging system of menopause. Consensus was reached for a 7-stage model.6 This consists of early, peak, UpToDate Patient information: Adjuvant chemotherapy and Premature menopause βΆ Effects on the heart βΆ Leukemia information: Adjuvant chemotherapy and trastuzumab (Herceptin) for early stage breast cancer VHL - Carrying on: the experience of premature menopause in women CONCLUSIONS: This study described the complexity of the experience of chemotherapy-induced premature menopause in women with early stage breast cancer and The Stages of Menopause at Menopause Insight Research the various stages of menopause development at Menopause Insight. Women who experience early menopause typically follow their mothers pattern. Early Menopause Links to information on early, or premature, menopause. are relevant to well being of women at every life stage from adolescence to midlife and beyond. BBC NEWS | Health | Menopause delay 'a possibility' This research is at a very early stage and needs to be confirmed or who are set to go through an early menopause, who lack follicles in their ovaries, SYMPTOMS A small degree of bladder control difficulty is common in the early stages of menopause, but a greater degree of difficulty can be The Stages of Menopause Menopause. The Stages of Menopause. The word menopause is used in popular span of time prior to perimenopause, perhaps as early as your mid-thirties. Menopause Early Stage. The beginning of perimenopause can begin in some women in their 30s, . Early menopause or surgical menopause (removal of ovaries) Menopause & Hormone Therapy - Stages of Menopause - Premature Understanding Menopause > Stages of Menopause > Premature Menopause Women who enter menopause early get symptoms similar to those of natural menopause, Menopause Early Stage. The beginning of perimenopause can begin in some women in their 30s, About 6 months before menopause estrogen levels drop significantly. Bone Mineral Density and Metabolism at an Early Stage of Menopause Bone Mineral Density and Metabolism at an Early Stage of Menopause When Estrogen and Calcium Supplement Are Not Used and without the Interference of Major Bone Mineral Density and Metabolism at an Early Stage of Menopause before the age of menopause. Spinal bone loss particularly. affected postmenopausal women, even at an early stage,. whereas femur sites were then spared. The Menopause Time Of Life Menopause or "change of life" is the time in a woman's life when . called the "silent disease" because there are no symptoms during the early stages. Symptoms of Early Menopause and Prevent Early Menopause To prevent early menopause symptoms and early stage of menopause, women should use bioidentical hormone replacement therapy to find permanent relief from |
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