Study Finds Menopause Symptoms Can Be Predicted

The number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.

Researchers now say they may be able to predict when that clock will wind down.

And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left.

According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason.

Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction.

"If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments."

Others reiterate, however, that the findings should be treated with caution.

"Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life."

According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000.

The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold.

The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause.

The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct.

While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated.

The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40.

SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction

early menopause tubaligation
Possible to get pregnant with tubaligation? - pregnancy-info.net - N01
I had all the symptoms and I too had a tubal ligation about 9 yrs ago. Unfortunately AF came . I guess early menopause could be a culprit.

Age at Natural Menopause and the Risk of Epithelial Ovarian Cancer
It has been postulated that early menopause may be associated with an . family history, and tubal ligation, evaluation of potential confounding by these

CAUSES
This is one of the most common causes of early menopause -- and often Similarly, some women experience premature menopause after tubal ligation (getting

The CPTwomens "Campaign to Inform"
Can Tubal Ligation Cause Menopause? "The Campaign to Inform" Human Rights, Civil Rights; Hormone Health, Hormone Shock, Early Menopause, Menopause

Post Tubal Ligation Syndrome (PTLS)
Castrative Menopause; Severe Hormone Imbalance; Ovarian Isolation (Post Hysterectomy, Post Tubal Ligation); Atrophic Ovaries; Hormone Shock

Symptoms of Post Tubal Syndrome
Side effects of Tubal Ligation Sterilization Early menopause after tubal ligations or hysterectomy : Does tube tying cause early menopause?

Premature Menopause Symptoms and Premature Menopause Weight Gain
Does tubal ligation cause premature menopause? Tubal ligation may cause an increased abnormal bleeding, cramps and disruption of the normal blood between

The Emma Goldman Clinic - Tubal Ligation
Couple considering tubal ligation should know that it is a major surgical In rare cases, premature menopause. Increased need for surgeries to control

INFORMATIVE: Tubal Ligation Reversal Problems - C01
Premature menopause DOES NOT appear to be part of the post tubal ligation syndrome but it may be an occasional complication of a sterilization procedure.

yikibiboqa: Premature Menopause Symptoms
C-section and Tubaligation for Premature menopause symptoms . zoloft and menopause premature menopause symptoms, early menopause symptoms - hormone

Tubal Ligation Reversal - Is Pregnancy Possible After Tubal Ligation?
A look at tubal ligation reversal for women who want to become pregnant, as well as for and other menstrual issues; symptoms of early onset menopause

pregnancy after tubal ligation and menopause >> Medical Questions
About a month after her birth I had a tubal ligation. to a specialist and came to the conclussion after test after test that I was in early menopause.

Pregnancy after tubal ligation and menopause >> Medical Questions
After my youngest child, I had a tubal ligation 10 years ago. specialist approximately 5 years later and found out I was going through early menopause.

Menopause
I have found information on the web that says that in some cases having a tubal ligation can and does cause early menopause. If any one has any advice or

Examples of Misconceptions: Sterilization
"Women must have hysterectomies after tubal ligation." egg from the ovaries to the uterus; it doesn't stop menstruation or bring on an early menopause.

Chronic UTIs Bodily Stressors
the tubal ligation is related to early. menopause; however, a review of the. literature reveals little evidence to sup-. port this concern (Riedel, Lehmann-

tubalig
(That is not early menopause.) I have not had a tubal ligation -- my husband had a vasectomy. (I did have a D & C, in my early 30's, which I now believe

Menopause & Perimenopause Ask The Expert
Question: When menopause starts after you have had a tubal ligation (10 yrs to mine and that eventually she was started on HRT to stop early menopause.

Menopause Symptoms ?
Surgeries such as hysterectomy and tubal ligation may cause menopause to occur earlier. The symptoms of perimenopause (early menopause) may be hot flashes,


early menopause tubaligation
evening primrose oil for menopause
american menopause north society
alternative estrogen menopause solution soy
hot flashes and menopause