Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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EarlyMenopause.com -> Pregnancy Tests Messages posted on the board are the opinions of the individual poster and do not necessarily represent the views of Early Menopause.com or the board Menopause - premature (early) menopause - Better Health Channel. Premature or early menopause occurs before the age of 40 years. with spontaneous premature menopause get pregnant, for reasons that are not yet clear. Menopause - Q & A - Better Health Channel. Women who experience early menopause will have a long period of postmenopausal life so the effects of oestrogen loss can be more serious. Early Menopause Links to information on early, or premature, menopause. Topics such as menopause, pregnancy, ageing, going into hospital BMJ BestTreatments :: Conditions :: Menopause :: What is it? It's worth talking to your doctor about contraception if you are having sex and don't want to get pregnant. Having an early menopause MedlinePlus: Premature Ovarian Failure Early Menopause Guidebook: Helping Women Make Informed Decisions(North American Ovarian Failure: Premature Menopause(American Pregnancy Association) Premature ovarian failure early menopause as the ovaries are extremely sensitive to the effects of . Thus the possibility of a pregnancy in young women suffering spontaneous POF About women's fertility during chemotherapy Temporary infertility; Early menopause; Being pregnant when your cancer is diagnosed; Ways to keep your fertility; Getting pregnant after treatment WomensHealthcareTopics.com, pregnancy week by week, endometriosis Provides information on women's health issues, signs of pregnancy, Afraid you might have early menopause? Having night sweats and hot flashes? EarlyMenopause.com (Powered by Invision Power Board) The place for general conversation about early menopause (EM) -- FULL meno BEFORE AGE 45, hoping for spontaneous pregnancy, or simply trying to adjust. Menopause: Pregnancy and Birth Control Herbs and Menopause · Menopause Diet · Early Menopause Risks of Pregnancy During Menopause A lot of perimenopausal are unaware of the facts surrounding Menopause: Early Menopause and Early Menopause Symptoms Explains the difference between early and premature menopause. Also discusses causes for early Epigee Women's Health · Online Pregnancy Resources Answers to FAQs and Articles about Perimenopause and early A menses after menopause -- can pregnancy occur? shown that the serum FSH level increases in the early--mid-follicular and early postovulatory phases in Early Menopause - Personal stories Early menopause (or premature menopause), personal stories of women with early I had missed periods, so off I went to do a home pregnancy test only to ivf-infertility.com | Premature menopause (PMM) Following transplantation, menstruation and ovulation resumed in the sisters with premature menopause. Spontaneous pregnancy has occurred in three women Premature menopause - WebMD You have unsuccessfully tried to become pregnant for more than a year. Your mother or sister experienced premature menopause. Early Menopause Treatment Thousands of women from 15 to 44 experience premature early menopause every year and experience This includes women with known or suspected pregnancy, What is Premature Menopause? Women who experience premature menopause and who want to become pregnant may be able to have a baby through a donor egg program. Premature Ovarian Failure: American Pregnancy Association A woman with premature ovarian failure, or premature menopause, All content is copyrighted by the American Pregnancy Association unless otherwise noted. |
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