Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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The Menopause Web Reference Lifelong dyspareunia may worsen around the menopause because of the loss of hormones causing further pain up to a complete avoidance of sex. RADIUM MENOPAUSE OR HYSTERECTOMY tion in sexual desire, dyspareunia and vaginal. discharge have been studied. MATERIAL. In all,. 157. cases. were studied, 101 who had the. menopause induced Sexual Dysfunction: Treat or Refer -- Sarrel 106 (4): 834 Physical examination may be particularly helpful in diagnosing atrophic vaginal changes, which frequently result in dyspareunia after menopause, Management of Libido Problems in Menopause The physiologic changes of menopause affecting sexual response are largely . Dyspareunia-related decrease in frequency of coitus can be the primary cause Symptoms and treatment of the menopause: urogenital changes The vaginal changes can lead to vaginitis, pruritus, dyspareunia, stenosis or loss of libido after the menopause. With low oestrogen levels in the late Pulse - Menopause Local oestrogen pessaries (use nightly for two weeks then about two to three times per week) will help deep dyspareunia. The British Menopause Society, ObstetricsandGynaecology Table of Contents OBSTGYN 705 Special Women's health and sexually transmitted diseases, menstrual disorders, pelvic pain and dyspareunia, vulva problems and vaginal discharge, menopause Menopause - Fulltext: Volume 13(5) September/October 2006 p 721 Dyspareunia increased significantly from early to late menopausal tissue integrity occur in a predictable manner with menopause and aging but the level Laboratory for the Biopsychological Study of Sexuality: Research The biopsychsocial profile of dyspareunia after menopause. Details; Development of an animal model of vulvar vestibulitis syndrome (VVS). Details Menopause Symptoms and Ovarian Aging and Senescence? Menopause There is strong evidence that menopause causes vasomotor symptoms. in relief of symptoms, including menopause associated dyspareunia, for most women. Exercise at Menopause: A Critical Difference Estrogen replacement therapy (ERT) also decreases the incidence of insomnia and dyspareunia at menopause and afterwards.5 Dyspareunia Menopause, the Q&A - May 26, 2007 Malaysia Star,drying and thinning (atrophy) of the vagina, incontinence, pruritis (vaginal itch) and dyspareunia (pain Menopause and its Management - Patient UK Menopause and its Management - Patient UK. A directory of UK health, Urinary and vaginal symptoms may include dyspareunia, vaginal discomfort and ScienceDirect - Fertility and Sterility : Lifestyles and Health Women who underwent surgical menopause reported suffering more from dyspareunia (22.67%) than women who underwent natural menopause or were pre-menopausal Dyspareunia: Sexual Dysfunction: Merck Manual Home Edition The pain of dyspareunia may be superficial, occurring in the genital area (in the If the cause is thinning and drying of the vagina after menopause, Menopause Forum - Possible Causes for Dyspareunia during Menopause Menopause Forum - Possible Causes for Dyspareunia during Menopause, Menopause information, health forums, medical questions, medical information, MedlinePlus Medical Encyclopedia: Sexual intercourse - painful Painful sexual intercourse; Dyspareunia. Definition Return to top If you are going through menopause and lubricants don't work, talk to your doctor Postgraduate Medicine: Dyspareunia in women Menopause: Dyspareunia in the perimenopausal or menopausal patient represents a unique opportunity for treatment. Hormones are fundamental to the health of Menopause, Atrophic Vaginitis and Sexuality One of women's strongest menopause-related complaints is dyspareunia. But, unless you make a point of asking, you may never find out about it. |
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