Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Menopause symptoms Menopause symptoms are as different and individual as women themselves. Some experience symptoms that their friends never do. The duration and severity of Osteoprotegerin: a valid new marker of bone turnover in post menopause duration of 15a9 years, in whom diseases and other age, menopause duration, bone turnover markers and BMD. values are given in Table 2. Annals of Oncology - Fulltext: Volume 13() October 2002 p 42 Age Age and duration of menopause as reliable criteria in the selection of DFI was significantly affected by the duration of menopause (<5 vs. 5-9 vs. PII: S0306-4530(97)00043-7 function of the duration of menopause. Women with a short duration of months a 6.1) were compared to women with a long duration of menopause (76.6 Relationships of serum estradiol levels, menopausal duration, and The relationship between serum estradiol levels and mood changes was found to be a function of the duration of menopause. Women with a short duration of What were your periods like before, during, after menopause What were your periods like before, during, after menopause. frequency and duration and how heavy? how old were you when this happened? Cancer Spectrum: Colditz et al., pp. 218-228. BMI during premenopause - 21.6) x duration of premenopause + (avg. BMI after menopause while using postmenopausal hormones - 24.4) x duration of Prevedia Clinical Study - Clinical Studies on Tribulus terrestris Twenty six patients were with the natural onset of menopause and the remaining 24 (48%) postoperative castration climacteric (Table 2). The duration of mRCT - Women's International Study of long Duration Oestrogen Public title, Women's International Study of long Duration Oestrogen after Menopause. Scientific title. Acronym, WISDOM. Disease/condition/study domain Women's Health, September 2001 The participants were 62 menopausal women (mean age, 52 years; duration of menopause, 2-12 years. They were classified into 2 groups depending on the Current smoking at menopause rather than duration determines the Background: Smoking has frequently been associated with early menopause. However, studies of this association have been inconclusive with regard to duration The Women's international study of long-duration oestrogen after The Women's International Study of long Duration Oestrogen after Menopause (WISDOM) developed from a joint initiative of the UK Medical Research Council Duration of menopause and behavior of malondialdehyde, lipids Duration of menopause and behavior of malondialdehyde, lipids, lipoproteins and carotid wall artery intima-media thickness. What is Menopause? - WrongDiagnosis.com Overview of Menopause as a medical condition including introduction, Duration of Menopause: Perimenopausal transition may last several years. Prognosis of Menopause - WrongDiagnosis.com Prognosis of Menopause including probably outcomes, duration, recurrence, The prognosis of Menopause may include the duration of Menopause, Menopause Facts Menopause, which normally occurs between the ages of 40 and 55, is a natural event in a but usually it tapers off, both in amount and duration of flow, Menopause Forum - Hot Flashes Duration Hot Flashes, Hot Flashes Duration, Menopause Forum , health forums, medical questions, medical information, medical symptoms, medical dictionary. Menopause Symptoms Vary in Scope, Duration During menopause, the body produces less estrogen and progesterone. Dr. Julie Mitchell notes that while some women have no symptoms, others might endure |
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