Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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JAMA -- Low-Fat Dietary Pattern and Risk of Invasive Breast Cancer Changes in food sources of dietary fat in response to an intensive low-fat dietary intervention: early results from the Women's Health Initiative. J Am Diet Changing Diet for Menopause This too is a good diet for menopause in that it is low in fat but rich in complex carbohydrates. That means the calories consumed are the 翜right莲 calories, St. Vincent Hospital Those who saw the greatest benefit from the low-fat diet were women who had . after menopause may have a slightly increased risk of ovarian cancer. What is a Low Cholesterol Diet Before the age of menopause, women have lower total cholesterol levels than . The TLC Diet. This is a low-saturated-fat, low-cholesterol eating plan that CNN.com High Fat, Low Carb Diet May Finally Be Getting Its Due ZAHN: On to some menopause news this morning, you brought all kinds of supplements with you this Study: Low-carb diet doesn't raise heart risk in women - USATODAY.com Eating a low-carb, high-fat diet for years doesn't raise the risk of heart for menopause symptoms, and on any history of smoking and heart problems. Maintain Your Health & Well-Being During Menopause | The Diet Channel Soy & Menopause: Women Are Eating Soy To Combat Menopause Other sources of calcium include low fat dairy products, beans, soy beans, sesame seeds, Intervention with a low-fat, high-carbohydrate diet does not Key Words: Menopause 立 mammographic density 立 low-fat diet 立 dietary fat The main reproductive risk factors for breast cancer are early menarche, Early sign of hip bone fracture/ weaken for menopause. Bone is a Early sign of hip bone fracture/ weaken for menopause to promote modest weight loss (low-fat diet and increased physical activity) compared with women The Menopause Diet: Lose Weight and Boost Your Energy The Menopause Diet shows you how to lose weight while increasing your energy level why a low-fat, high carbohydrate diet is like digging your own grave, Food/Diet Therapy, Menopause and Hormone Replacement Therapy Some scientists theorize that when eaten early in life, as in Japan, A low-fat, high-fiber diet will help the body to adjust more easily to changing Low-Fat, High-Carb Diet Does Not Affect Timing of Menopause Low-Fat, High-Carb Diet Does Not Affect Timing of Menopause CME List factors associated with early and late menopause in women with high mammographic Low-Fat Diet Not a Cure-All: Nutrition Source, Harvard School of Of these, 19541 were randomly assigned to follow a low-fat diet. of breast cancer after menopause, and that staying slim after menopause is an effective The Menopause Diet - Flush Fat and Toxins Choose from over 300 Low Glycemic, Low Fat, High Fiber, Low Sodium., The Menopause Diet Mini Meal Cookbook The decadent diet cookbook for Boomer Babes Ovarian Cancer Odds Lowered with Fiber, Low-Fat Diet Older women who stick to a low-fat, high-fiber diet could cut their odds for after menopause may have a slightly increased risk of ovarian cancer. ACS :: Studies Find Little Cancer Benefit in Low-Fat Diet for Three new studies suggest that eating a low-fat diet doesn't have a big an impact on cancer or heart disease in women past menopause. ACS :: Low-Fat Diet May Stall Breast Cancer Recurrence Eating a low-fat diet is known to help the heart, but now there's evidence it About one-third of women past menopause develop ER-negative breast tumors, Study shows a low-fat diet may not reduce breast cancer risk A large multi-center, multi-year study earlier this year on whether eating a low-fat diet after menopause can reduce a woman's risk of breast cancer didn't |
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