Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Fitness Articles ::: Fertility & Pregnancy : Fertility pill to In a recent news published, fertility experts claim to have identified a protein which could be harnessed to delay the menopause. The discovery raises hopes Fertility pill that could delay menopause Fertility experts claim to have identified a protein which could be harnessed to delay the menopause. The discovery raises hopes that drugs could be Elixir News | Pill to delay menopause may be on way, says top UK London: A leading fertility expert has revealed that new drugs are being developed that would delay the menopause. Can I delay menopause? Can I delay menopause? ANSWER:. Menopause is a natural process in women that cannot be delayed. It is officially defined as one year past your last SG KE TOI Scientists making pill to delay menopause SG KE TOI Scientists making pill to delay menopause. Knowledge Ganesh Srinivasan's Exchange. CBS.com SCHIFF: While it might not be possible to delay menopause, multiple studies show that cigarette smoking triggers early menopause. Women who smoke generally Human egg trials could delay menopause - News - Manchester Evening Human egg trials could delay menopause. 5/ 5/2005. SCIENTISTS have made a breakthrough that could lead to delaying a woman's natural menopause by more than Pill may help delay menopause | Special reports | Guardian Unlimited Pill may help delay menopause. Dan Bell Monday June 11, 2007 The Guardian. Women may soon be able to prolong their childbearing years by taking a pill to Hormone pills 'delay menopause': Sci-Tech: News: News24 News24: Sci-Tech: News: Hormone pills 'delay menopause': A new survey suggests that hormone pills might postpone but not prevent menopausal symptoms. Scientists Claim to Find Cells That Restore Egg Production The discovery could also lead to ways to prevent, delay or reverse menopause, perhaps by stimulating dormant cells in the bone marrow or "tweaking" the Preventing Menopause: You can prevent menopause! The information needed to prevent or delay menopause for at least thirty years, thus improving our sex lives, overall health, and reducing our heart, colon, BBC News | HEALTH | Pill project to delay menopause Scientists are trying to develop a contraceptive pill which would extend a woman's childbearing potential. BBC NEWS | Health | Menopause delay 'a possibility' Human eggs have been developed from ovarian stem cells for the first time, US researchers have revealed. Menopause, HRT, and Nutrition - Nutri-Notes Newsletter Vol 3, #6 Hormone replacement therapy (HRT) is hormonal replacement to delay menopause, which involves administration of estrogen and sometimes synthetic progesterone Understanding Menopause We can delay menopause by strengthening the kidney chi, retaining the vital fire and water elements in the body. Yin (water/female) and Yang The Straight Dope: Does use of The Pill delay menopause? The Straight Dope: Does use of The Pill delay menopause? Scientists develop pill to delay the menopause | the Daily Mail New drugs are being developed that could stave off the menopause, it has been revealed. New procedure may delay menopause New procedure may delay menopause. Last Updated: Friday, November 10, 2000 | 11:51 PM ET. CBC News. Women may no longer have to worry about their biological |
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