Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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IngentaConnect Ovarian function, therapy- oriented definition of Induced Menopause Definition. Insomnia Definition of Insomnia. Isoflavones Isoflavones definition Definition of perimenopause, period around menopause Menopause_Glossary Definition of menopause in the Online Dictionary. Meaning of menopause. What does menopause mean? menopause synonyms, menopause antonyms. Menopause Definition Ovarian function, therapy- oriented definition of menopause and climacteric. Author: Utian W.H.. Source: Maturitas, Volume 22, Number 1, June 1995 , pp. What is premature menopause? Find the definition for premature The term "menopause" comes from two Greek words that mean "month" and "to end," in other words, it translates as "the end of the monthlies. What is menopause? Find the definition for menopause at WebMD premature menopause. Font Size. A · A · A. failure of cyclic ovarian function before age 40. Syn: premature ovarian failure Early Menopause - Home Permanent cessation of the menses due to ovarian failure; termination of the menstrual life. Definition of menopause - NCI Dictionary of Cancer Terms menopause The time of life when a woman stops getting her period, or menstruating. This is sometimes called. menopause - definition and pronunciation Definition of Early Menopause. Menopause before the age of 40 is termed 'premature menopause'; Menopause between the age of 40 and 45 is termed 'early menopause - Definition from the Merriam-Webster Online Dictionary A woman is in menopause when she hasn't had a period for 12 months in a row. Also called change of life. Previous Definitions:, meningeal metastasis, Definition of Menopause - Nishmat Women's Online Information Center Definition of menopause from the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word games. Definition of halide,menopause,myofibril,confusion,external nares Definition of Menopause. Menopause is the permanent cessation of menstruation due to loss of ovarian activity and the depletion of follicles (the Definition of Menopause -- eCureMe.com The average age of menopause is around 52 years. Definition of menopause medical term menopause define menopause definition of menopause what is the Welcome to the Australasian Menopause Society Menopause, or climacterium, marks the completion of a woman's childbearing years and the cessation of menses (menstrual cycles), as the ovaries slow down News - New Breast Cancer Guidelines Define Menopause: Presented at To help ensure a standardized definition of key words used in the field, the International Menopause Society (IMS) commissioned a project through its Menopause, definition, menstruation, perimenopause -- RealAge New Breast Cancer Guidelines Define Menopause: Presented at NCCN. Natural menopause definition - Menopause: Menopausal Health and Definition of Menopause Menopause is the phase of a woman's life when she no longer experiences menstruation. Menopause is usually confirmed once a woman Menopause definition - Menopause: Menopausal Health and Medical Definition of Natural menopause. Natural menopause: Natural menopause occurs when the ovaries naturally decrease their production of the sex hormones menopause: Definition and Much More from Answers.com Menopause: The time in a woman's life when menstrual periods permanently stop; it is also called the "change of life." Menopause is the opposite of the |
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