Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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PCOS and Ovarian Cancer: Early Detection of Symptoms is Essential Ovarian cancer usually develops after menopause. Although itâ™s not known for sure whether benign ovarian cysts or polycystic ovaries develop into Ovarian Problems: Ovarian Cysts - treatment Even if the ovary is badly damaged by the cyst and only a small part remains, Even after menopause, the ovaries continue to produce small amounts of Ovarian Cancer: Cancers of the Female Reproductive System: Merck In young women, enlargement of an ovary is likely to be caused by a noncancerous fluid-filled sac (cyst). However, after menopause, an enlarged ovary is Ovarian Cysts, Menopause - Power Surge This type of cyst usually goes away on its own after a few weeks. However, it can grow to almost four inches and may bleed or twist the ovary and cause pain Ovarian Cyst -- familydoctor.org If you're past menopause and have an ovarian cyst, your doctor will A laparotomy uses a bigger incision to remove the cyst or possibly the entire ovary. Functional Ovarian Cysts - Exams and Tests - Yahoo! Health Some doctors will recommend removing the ovaries when any kind of cyst develops on an ovary after menopause. However, experts are researching the best way Ovarian Cyst After Menopause Article Since typical ovarian cysts are usually the result of cyclical reproductive functions, a cyst on ovary after menopause needs to be monitored to assure that ParkerMD.com Ovarian Cysts However, because the incidence of ovarian cancer increases with age, any cyst or growth in the ovary after the menopause should be fully evaluated. Ovarian cysts - CNN.com Cystic ovarian masses that develop after menopause may be cancerous (malignant). Some cysts can be removed without removing the ovary in a procedure Ovarian cancer - CNN.com However, cysts that form after menopause have a greater chance of being cancerous. . be if you turn out to have a noncancerous abnormality on your ovary. Ovarian Cysts symptoms treatments causes After menopause, the risk of ovarian cancer increases. whether he or she plans to remove just the cyst, the cyst and the ovary, or to do a hysterectomy. |
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