Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Study links menopause to weight gain Study links menopause to weight gain from DailyIndia.com, an essential role in controlling energy balance, body fat distribution and normal body weight. Nutrition Notes: Making it through menopause - Nutrition Notes Women are right to be concerned about weight gain. A recent Finnish study found that each two pounds of weight gained during menopause raises the risk of Weight Gain Prevention among Women -- Levine et al. 15 (5): 1267 After controlling for initial BMI, increasing dietary restraint (Ăź = 0.15, .. (2003) Lifestyle intervention can prevent weight gain during menopause: News Release: Revealing estrogen's secret role in obesity Scientists long have sought to understand how changes in hormones during menopause could account for the increase in appetite and accompanying weight gain Annals of Epidemiology : Weight Change in Relation to Natural Weight gain was significantly higher in women who remained premenopausal as compared with those who had natural menopause after controlling for age and Weight Gain in Menopause Many women are concerned about weight gain that is typically associated with menopause. Although the average woman gains two to five pounds during the Weight gain in pregnancy Breast cancer and pregnancy weight gain; Controlling your weight . any excess 'baby weight' after having their baby and especially, before the menopause. Women's Health and Fitness During Menopause - Menopause and Your Diet The Importance Of Fitness During Menopause Menopause Weight Gain - Why You with menopause by eating healthy, controlling your caloric consumption and Menopause Controlling Weight Gain. Many women need to increase physical activity and reduce caloric intake before and after menopause. Weight gain is common during Slowing Excess Weight Gain In Childhood Appears To Reduce Adult Excessive Weight Gain During Pregnancy Can Increase Breast Cancer Risk, could triple a womanâ™s risk of developing breast cancer after menopause, Lifestyle Intervention Can Prevent Weight Gain During Menopause The most consistent behavioral factor contributing to weight. gain during menopause is decreased leisure-time physical activ-. ity (4,7). Postgraduate Medicine: Weight gain during menopause Weight gain during menopause: is it inevitable or can it be prevented? . After controlling for weight change, the effect of estrogen on reducing waist How to lose perimenopause weight gain through diet, weight loss Perimenopause weight loss attempts - and stopping additional weight gain during perimenopause and menopause - are near impossible with a sluggish metabolism Would you like to lose premarin weight gain with weight loss patch For some reason unknown to researchers, weight gain tends to occur in women during and after menopause whether they choose hormone replacement therapy Facts About Weight Gain and Menopause Additional weight gain during menopause can be a result of over eating due to This makes controlling weight gain at menopause very important for women. Menopause and Weight Gain - What's the Connection? Controlling and preventing weight gain during menopause is important for many reasons. During mid-life, a womanâ™s body tends to change from a pear shape Weight Loss Success: Controlling Midlife Weight Gain Controlling Midlife Weight Gain. Youâ™ve remained relatively the same weight for most of your Causes of Weight Gain During menopause and perimenopause, Weight Gain During Chemotherapy Although menopause does not necessarily mean a woman will gain weight, it seems only logical that controlling chemo weight gain is of great importance. Menopause Weight Gain - What Causes Menopausal Weight Gain in Women? Recent studies on weight gain during and after menopause weight gain. In addition to playing a huge roll in controlling weight, it |
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