Study Finds Menopause Symptoms Can Be Predicted

The number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.

Researchers now say they may be able to predict when that clock will wind down.

And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left.

According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason.

Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction.

"If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments."

Others reiterate, however, that the findings should be treated with caution.

"Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life."

According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000.

The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold.

The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause.

The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct.

While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated.

The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40.

SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction

code icd9 perimenopause
Factors Affecting Prophylactic Oophorectomy in Postmenopausal
There was no ICD-9 code for laparoscopically assisted vaginal hysterectomy during the time of the study. As performed in a previous analysis, patients coded

Clinical Guidelines: Dilation and Curettage (D&C)
ICD-9 Diagnosis, including, but not limited to: Perimenopause: the time just before and after menopause. Polycystic ovarian syndrome (PCOS): a condition

Bone Mineral Density Measurement and Treatment for Osteoporosis in
tient study fracture ICD-9 codes. This method of fracture as-. certainment was validated through .. scribed to preserve bone vs to treat perimenopausal

REPORTS
of their death (ICD-9 174) and control . breast (ICD-9 174) as the underlying cause of death. 20-44 years of age, a perimenopausal group aged

LCD: LUTEINIZING HORMONE-RELEASING HORMONE (LHRH) ANALOGS (L3602)
ICD-9-CM code listings may cover a range and include truncated codes. ICD-9 Codes that DO NOT Support Medical Necessity Asterisk Explanation

Breast Vascular Calcification and Risk of Coronary Heart Disease
heart failure (ICD-8 code 427 and ICD-9 codes. 428, 402.01, 402.11, and 402.91). . Premenopausal or perimenopausal. 1889 (15). 6 (1). Postmenopausal

The Liberal Democrats ALTER: Comment on Letter in Guardian
Aloha - effexor menopause - peri menopausal bleeding - menopause the musical orlando florida - perimenopause - pre menopause symptom - icd 9 code for

Business Opportunity - Patient Reimbursements
Commonly Used ICD-9 Codes. ICD-9 Diagnosis *252.0 Hyperparathyroidism Then all codes listed are acceptable for high risk (perimenopausal) individuals

8610640 J Bone Miner Res 0884-0431 American Society for Bone and
( 14 ) We excluded fractures associated with ICD-9-CM trauma codes (ICD-9-CM E800-E879 .. Eiken P 1997 Site of osteodensitometry in perimenopausal women:

The age distribution, rates, and types of surgery for stress
SUI surgical rates were similar for perimenopausal and . Table 3 ICD-9-CM diagnosis codes for morbidities associated with stress urinary incontinence

FRONT "HealthNow New York Inc., Upstate Medicare Division
ICD-9-CM code listings may cover a range and include truncated codes. Further, these ICD-9-CM codes can be used only with the conditions listed in the

18.4 "2000 (11) November - Provider Bulletin" IBM Library Server
ICD-9-CM code listings may cover a range and include truncated codes. A claim submitted without a valid ICD-9-CM diagnosis code will be returned as an

icd opinions on Ljfind
Fig disappear complex solar hebdomad cm 845 01 planet code medical symptom graph icd 9 code for perimenopause icd 9 coding and transcription jobs paragraph

MTV Super Select
Buenas dias - moodswings and menopause - swollen lymph nodes menopause - icd 9 code for perimenopause - night sweats and premenopause - menopause and

Infertility
ICD-9 codes not covered for indications listed in the CPB (not all-inclusive): .. Clinical challenges of perimenopause: Consensus opinion of The North

Account Services
Indicate which hormones to test and reference an ICD-9 code if applicable for (Bone Loser) and perimenopause (Transitions) along with tabletop displays,


code icd9 perimenopause
after doctor menopause spotting
age of perimenopause
anxiety menopause
information perimenopause