Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Menopause - Fulltext: Volume 11(6, Part 2 of 2) November/December Menopause is characterized by hormonal changes because of disappearance of . that even absolute changes in clitoral volume do not differ between groups. 88.05.06: Áœthe Effect of Hormones on Female Sexuality and MenopauseÁ« The vestibule of the vagina is situated posterior to the clitoris. The primary cause of menopause is due to the changes sent out by the endocrine system WomenHealth - Obstetrics and Gynecology A year or two before menopause, you may notice changes in your menstrual cycle. Others feel discomfort in the clitoris, part of the female genitals Testosterone specific--male type hair growth, oily skin and acne, enlargement of the clitoris, changes in the voice, coarsening the skin Resource Center > Impact of Cancer and Menopause on Women's Sexuality Changes in vaginal sensation, shape and lubrication also are common. Chemotherapy and/or surgery may throw a woman into early menopause, and some patients Introduction, Female Genital and Sexual Disorders, THE MERCK These changes, many the result of menopause, help set the stage for The clitoris, located between the labia minora, is a small protrusion that is very Menopause - Health & Wellbeing Menopause 300x150 Image source: IStockphoto. Signs of 'the change' The labia and clitoris may decrease in size because they lose some of their fatty MTV Super Select Buenas dias - premenopause symptoms - post menopause vaginal bleeding - menopause detroit - clitoris changes in menopause - vaginal dryness best regards Sex matters with Dr Thomas Stuttaford and Suzi Godson - Health The full extent of the clitoris was identified only seven years ago, But . . . if the changes at menopause were a direct result of declining blood flow When Menopause Dampens Desire - MSN Health & Fitness - Women's Health Q: What happens to your body sexually after menopause? Slight shrinkage of the vagina, labia and clitoris;; Changes in clitoral sensitivity (may be Age-Related Factors that Impact Sexual Functioning | Sexuality in 1999; Avis et. al 2000) research on the impact of menopause and sexual Clitoral changes from aging include shrinkage, a decrease in perfusion, |
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