Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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IngentaConnect Factors associated with total cholesterol levels in Objective To obtain data on correlates of total cholesterol (TC) levels in women around menopause attending menopause clinics in Italy. Atherosclerosis : Effects of age at menopause on serum cholesterol Another possible interpretation is that the effects of aging on serum cholesterol after menopause is not linear but rather flattened after a certain age. Elevated cholesterol due to Menopause? - Gastroenterology - MedHelp High blood cholesterol and triglycerides was 197. (was not in menopause) Never have had any health problems of this type and my doctor feels trying a Menopause and Serum Cholesterol: Differences between Blacks and An interaction term in a linear regression model confirmed a racial difference in the total cholesterol association with menopause (p < 0.02). Menopause - Causes, Symptoms and Treatment for the Hormonal Around the time of menopause, women often lose bone density and their cholesterol may worsen, increasing their risk of heart disease. Menopause Estrogen and Cholesterol: As Women Age Cholesterol A young woman's estrogen raises good HDL cholesterol. After 50, HDL levels drop and bad LDLs, triglycerides, and heart disease increase. HEALTH; Menopause Linked to Cholesterol Changes - New York Times LEAD: Women's blood cholesterol levels worsen abruptly after menopause, and this may help explain their increasing risk of heart attacks, Heart attack, stroke skyrocket after menopause: lowering Heart attack, stroke skyrocket after menopause: lowering cholesterol and blood pressure through a healthy diet and regular exercise can reduce your risk Your Menopause Type - Cholesterol Women: Find a local Professional who carries Menopause Type Formulations Pathway: Cholesterol à Pregnenolone + Isocaproaldehyde From Dr. JoAnn Manson: Impact of Menopause on Cholesterol "I've been shocked to discover that I have developed high cholesterol ⓠcould this be related to menopause? And will it go down on its own?" Not So Strange Bedfellows: Menopause And High Cholesterol Not So Strange Bedfellows: Menopause and High Cholesterol: Denise Janosik, MD, associate professor of internal medicine at Saint Louis University School of High cholesterol linked to menopause | Health Link | KING5.com High cholesterol linked to menopause Dr. William James howard says years of study show menopause does affect cholesterol. Women's Health: Coping With Menopause They are good choices to decrease heart disease risk in women with high cholesterol readings. Summary At menopause, you need to take a comprehensive look at Effects of Menopause on Trends of Serum Cholesterol, Blood Background To elucidate the impact of menopause on coronary risk factors, we determined the trends of serum cholesterol (mg/dL), blood pressure (BP, mm Hg), The increase in cholesterol with menopause is associated with the The mean increase in cholesterol with menopause in women with the APOE3E3 genotype was 0.67 mmol/L (95% CI, 0.61-0.72 mmol/L). In women with the APOE2E3 Natural Approach to Menopause This is because before a woman reaches menopause, the higher levels of estrogen protect against LDL ("bad") cholesterol. During menopause, this protective Effects of Menopause on Trends of Serum Cholesterol, Blood Serum cholesterol in women with natural menopause increased significantly . An increase in serum cholesterol precedes natural menopause by {approx} Menopause Message Boards and Menopause Forums -- Power Surge As I go through menopause my cholesterol levels have skyrocketed, even though I am .. If you have any questions regarding cholesterol and menopause, |
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