Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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THE MERCK MANUAL OF GERIATRICS, Ch. 119, Menopause This transitional phase is termed perimenopause or the climacteric. Skin perfusion increases about 1.5 minutes before the sensation and 6 minutes before signs of menopause Signs 1-14 are the major, most common signs of peri-menopause and menopause; Electric shock sensation under the skin and in the head (see note) Amethyst Journey: Topic: Perimenopause Skin Some women experience extremely dry skin or the sensation of Áœcrawling bugs.Á« The skin feels tight, dry and may even burn. Joint/Muscle Perimenopause, Hormone Therapy Á“ Expert Advice Perimenopause - The North American Menopause Society provides expert An increased pulse rate and a sensation of rapid heart beating may also occur. Balancing Hormones and Skin Electric shock sensation under the skin and in the head Tingling in the extremities Gum problems, increased bleeding Burning tongue, burning roof of mouth, 34 Menopause Symptoms - all about each menopausal symptom. 34 menopause symptoms. Learn how to identify menopause and perimenopause symptoms. Electric Shock Sensation Under the Skin And In The Head: Hotflash! News - Common Perimenopause Signs and Symptoms Some gals experience "crawling skin"- their skin feels tingling, dry , maybe a burning sensation. Joint and muscle aches and pains. Digestive disturbance Symptom: Tingling - CureResearch.com Introduction: Abnormal nerve sensations such as pins-and-needles, tingling, burning, prickling or similar feelings are all known as "paresthesias". Apria - resources - Community I have had this sensation of burning under my skin for about a month now, thing and have been told it is similar to a hotflash. Are you in perimenopause burning sensation of skin and hands and groin >> Medical Questions Post Posted: 11/03/06 - 16:24 Post subject: burning sensation of skin and hands and groin, Reply with quote Uteran sensations during perimenopause Burning skin sensations >> Medical Questions, Weight Loss Posted: 02/22/07 - 21:50 Post subject: Burning skin sensations, Reply with quote burning sensations in bladder · Uteran sensations during perimenopause Prickling and burning skin--is this perimenopause? Anyone else Archive Prickling and burning skin--is this perimenopause? little stabbing pains at mainly the temple, but not the prickling and burning sensations. Menopause Message Boards and Menopause Forums -- Power Surge do any of you who get he burning skin sensation also get it in your nosae and mouth? .. Board Discussions, |-- Am I Starting Perimenopause? Power Surge Forums > Burning and numb skin sensations from anxiety I also have had this burning sensation for years. It is always on one side of my body only. It starts usually at my buttocks and goes down my leg. could these be perimenopause symptoms - Menopause - MedHelp This is a discussion on MedHelp about could these be perimenopause symptoms. Since June I intermittently get a burning sensation on the skinActinic Menopause Symptoms Page..hot flashes, night sweats, itching Electric shock sensation under the skin and in the head 30.Tingling in the extremities, 31.Gum problems, increased bleeding 32.Burning tongue, burning roof WOMENS-HEALTH Messages for June, 1998: Re: Symptoms of Peri-menopause Electric shock sensation under the skin and in the head (see note) 30.Tingling in the extremities, (see note) 31.Gum problems, increased bleeding 32.Burning 35 Symptoms of Menopause This list of common symptoms that occur during perimenopause and menopause was Electric shock sensation under the skin and in the head (see note) Causes of Symptom: Tingling - WrongDiagnosis.com deficiency - abnormal skin sensations; Blepharitis - burning eye sensation Penile candidiasis - penis burning; Perimenopause - facial tingling |
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