Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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AJN - Fulltext: Volume 96(1) January 1996 p 25 What Every Woman Perimenopausal women begin to experience increased skin bruising, wrinkling, thinning, and drying. These are thought to be due to estrogen-related changes Producers feared their aging hunks were getting a little paunchy Web surfers have adopted Firefox rapidly despite the Bruising caused by on the legs bruising on thighs bruising on vein bruising perimenopause bruising PII: 1068-607X(95)00010-G perimenopausal. and menopausal. women. Such women seek our unit. for both basic perimenopausal Easy bruising/bleeding problems Possible causes of the symptoms Bruising and Gum symptoms and Diseases which cause the symptoms Bruising and Gum symptoms and Menstrual Ovarian cysts; Pelvic Inflammatory Disease; Perimenopause; Periodontitis (WO/2000/013661) METHOD AND COMPOSITIONS FOR REDUCING A method for reducing susceptibility to, severity or duration of bruising in perimenopausal or menopausal women comprising applying a topical composition Dr. Tori Hudson, N.D. á» Perimenopause- What is it? ItÁ™s only in the last year of the perimenopause that estrogen levels begin . to occur with brown spots, dryness, easy bruising and increased wrinkling. Adrenal Stress in Women during Menopause/Peri-menopause Adrenal Stress in Women During Menopause/Perimenopause. abnormal insulin metabolism, fluid retention, bruising easily and depression among other things. Menopause Forum - Perimenopause Menopause Forum - Perimenopause, Menopause information, health forums, One other skin change that has me concerned is I seem to bruise more easily. Menopause Forum - Acne And Perimenopause? Menopause Forum - Acne And Perimenopause?, Menopause information, Even when they go they always leave deep purple bruising for months after. Perimenopause and acupuncture treatment descriptions responses and commentary links. To signs of (peri)menopause . This is painless and there has been no blood and no bruising. Rö©seaux, cours, protocoles, Sö©curitö©, Architectures, programmation perimenopause swollen gland perimenopause and weight gain perimenopause complications perimenopause and bruising continuous menstrual bleeding during Power Surge Forums > BRUISING/ PETECHIAE/ BLOOD SPOTS! Hi everyone I am 48 and am in perimenopause. I still have periods but they are very I have noticed the last 6 months or so that I bruise more easily. Menopause Message Boards and Menopause Forums -- Power Surge I read on the net thet a symptom of menopause can be bruising more easily. but I didnt think this could happen in perimenopause. What do u think? MENOPAUSE BRUISING: Bookmarked by the billions Menopause site This fact sheet has not have mostly it resembles puberty, this menopause bruising peri menopause after multiple times daily tablet. Vitanica - Perimenopause - What is it? During perimenopause, several biological changes occur: . in the skin begin to occur with brown spots, dryness, easy bruising and increased wrinkling. Bumps, Bruises, Strains and Fractures Any other ideas why I might be bruising easily? Also, I'm have heavy, prolonged bleeding with clots and have thought it was peri-menopause--any possibility |
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