Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Risk Management: Surgical Menopause It reviewed women who took HRT, ERT or a placebo after natural menopause. women who underwent surgical menopause due to risk-reducing oophorectomy, Healthnotes Newswire: Testosterone Improves Sexual Function in Healthnotes from G.Baldwin and Co: Healthnotes Newswire: Testosterone Improves Sexual Function in Women After ?Surgical Menopause? WOMENS-HEALTH Messages for October, 1999: HRT vs. oral HRT vs. oral contraceptive after surgical menopause. From: Char (anonymous@obgyn.net) Tue, 12 Oct 1999 18:17:44 -0500 (CDT) Surgical Menopause Increases Salt Sensitivity of Blood Pressure Although all of the women remained normotensive, the prevalence of salt sensitivity was significantly higher after surgical menopause (21 women; Hormones and Quality of Life after Surgical Menopause Editorial Hormones and Quality of Life after Surgical Menopause. WULF H. UTIAN, M.D., Ph.D. 975. Q. UALITY OF LIFE. (QOL) is a term that is both an Risk for Low Sexual Desire Increases in Women after Surgical Menopause New research shows women who experience hysterectomy and oophorectomy are at higher risk for low sexual desire A cross-sectional survey of European women Migraine,Low body temp after surgical menopause - Menopause - MedHelp Migraine,Low body temp after surgical menopause. This forum is for questions and support regarding menopause issues such as: Depression, Hormone Replacement Natural versus surgical menopause implications for the and 34 women after a surgical menopause. The onset of a. natural menopause was taken as the time . increased after surgical menopause cannot be explained Longevity after early surgical menopause-the long-term effect of a Longevity after early surgical menopause-the long-term effect of a permanent cessation of reproductive function and female sex hormone loss. Testosterone may raise sexual desire after surgical menopause | OB Testosterone may raise sexual desire after surgical menopause from OB/GYN News in Health provided free by Find Articles. Blood pressure and metabolic profile after surgical menopause Blood pressure and metabolic profile after surgical menopause: comparison with fertile and naturally-menopausal women. E Casiglia1, G Ginocchio2, Medical News: Testosterone May Patch Up Desire After Surgical Testosterone May Patch Up Desire After Surgical Menopause women with hypoactive sexual desire disorder following surgically induced menopause experience College Pharmacy Discussions - HRT after surgical menopause Seven (7) years ago, I had a complete hysterectomy (including ovary removal), which placed me into surgical menopause at the young age of 28. IngentaConnect Biochemical markers of bone turnover after surgical Determinations were performed after 3 months of surgical menopause and -CTX is the most sensitive marker of bone resorption after surgical menopause. IngentaConnect Restoring Sexual Desire After Surgical Menopause Restoring Sexual Desire After Surgical Menopause: Update on Assessment and Management. Author: Simon, James A.1. Source: Current Women's Health Reviews Bone : Biochemical markers of bone turnover after surgical In addition, after surgical menopause, PINP showed the highest increment, with a mean percent increase of 101%, while BAP, TAP, BGP, and PICP showed The advantages and disadvantages of natural and surgically-induced With regard to osteoporosis, the rate of bone loss right after surgical menopause is higher than it is for natural menopause (14). Osteoporosis Prevention after Surgical Menopause GOG-215 Searching for New Ways to Improve Bone Health After Surgical Menopause, Osteoporosis Prevention after Surgical Menopause Life after gynecologic cancers: Surgical or premature menopause Frequently Asked Questions about dealing with surgical menopause after treatment for gynecologic cancer. |
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