Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Aching joints, Muscle aches - Alternative remedies The Menopause Self Help Book by Susan M. Lark, M.D., It is not wise to ignore these aches and pains. Early treatment can often bring about a cure and Sore muscles, Aches & Pains - Alternative remedies Physical distress seems to be more common during menopause. but is not necessarily a helpful approach for those who have fibromyalgic aches and pains. Maryon Stewart: Joint Aches and Pains During Menopause If joint aches and pains manifest during the menopause, it is recommended that glucosamine is taken, a natural substance found abundantly in the body. Family Planning NSW: Sex Matters: FAQs: I am a middle aged woman Yes, aches and pains are some of the things that some women experience at menopause. It is not actually muscle deterioration. The exact cause is not known, The Menopause, Naturally - Symptoms Many women suffer from general aches and pains during the menopause. It is unclear whether they are caused by the menopause, but they often occur along with Fibromyalgia - muscle changes during menopause - Susun Weed Your body knows more about menopause than your doctor does - empower yourself the "Bring me your soreness. Bring me your pain. Bring your aches to me. Osteoporosis, Menopause and Osteoporosis, Osteoarthritis, Joint treating menopause. Chat with other women about joint aches and pains and about osteoporosis. Every week a new guest transcript in the Power Surge Library Joint pain and muscle stiffness â” a natural approach Almost all women in perimenopause and menopause suffer from joint pain or including inflammation in the joints and the resulting aches and pains. Aches & Pains Treatment - Guide to Perimenopausal Aches & Pains Aches and pains will become a more prominent part of your life as you move closer to menopause. The good news is that dancing will be part of your new BBC - Health - Womens health - Menopause What happens to your body during the menopause. Aches and pains - low levels of oestrogen can lead to an increase in aches and pains. Menopause - symptoms, effects and information on HRT The typical symptoms of menopause are particularly hot flushes and menstrual thinner, drier skin, hair and brittle nails; aches and pains in your joints |
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