Study Finds Menopause Symptoms Can Be PredictedThe number of eggs left in a woman's ovaries are like the grains of sand in an hourglass, ticking away the hours on her biological clock.Researchers now say they may be able to predict when that clock will wind down. And while doctors can't actually count the number of eggs in an ovary, they can measure ovarian volume. British researchers say there's a direct correlation between the two, and by measuring ovarian volume with transvaginal ultrasound, doctors should be able to predict when menopause will set in and how many fertile years a woman has left. According to the study authors, this information will revolutionize the care of women looking for assisted reproductive technologies, including those who were treated for childhood cancers as well as women who want to put off starting a family for whatever reason. Although information still needs to be validated in clinical studies, its benefit is most likely to start with women who are being treated for cancer and women attending fertility clinics, said Tom Kelsey, co-author of the study appearing June 17 in the journal Human Reproduction. "If women looking for some sort of assisted conception and their physicians know that they've got a long time till menopause, then you could plan for a range of treatments," said Kelsey, who is a senior research fellow at the University of St. Andrews in Scotland. "If you knew menopause was likely in four to five years, you'd plan a different set of IVF [in vitro fertilization] treatments." Others reiterate, however, that the findings should be treated with caution. "Should a young woman who is 30 years old go for a test to figure out whether she's got three, five or 10 years left on her fertility? Should she make career decisions and life decisions? Are these data good enough to make those determinations?" asked Dr. Alan Copperman, director of reproductive medicine at Mount Sinai Medical Center in New York City. "The answer is obviously no to all of those questions. The predictive value of this test is not good enough to go and tell someone to change their life." According to the article, eggs form in a female's ovary while she is still in the womb, peaking at several million about halfway through gestation and then starting a continuous decline. At birth, there are several hundred thousand and, when menstruation begins, about 300,000. At about age 37, a woman has about 25,000 eggs left, and at menopause only about 1,000. The time at which menopause sets in is widely believed to be based on the number of eggs reaching a critically low threshold. The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause. The study authors are negotiating with a medical school to set up clinical trials. The idea would be to follow women to see if their predictions were indeed correct. While these authors have come up with a tool to potentially help women plan their lives, a second study in the same issue of Human Reproduction warned that women might not want to leave it too late. Assisted reproductive technology (ART) could not be relied upon to fully compensate for lack of natural fertility after the age of 35, the article stated. The authors used a computer simulation model to determine that the overall success rate of assisted reproductive technology would be 30 percent for those attempting to get pregnant from age 30, 24 percent for those trying from age 35, and 17 percent from age 40. SOURCES: Tom Kelsey, Ph.D., senior research fellow, University of St. Andrews, St. Andrews, Scotland; Alan Copperman, M.D., director, reproductive medicine, Mount Sinai Medical Center, New York; June 17, 2004, Human Reproduction |
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Menopause and Perimenopause - Menopause - Revolution Health Revolution Health is a trusted source for menopause and perimenopause information, For more information, see the topics Abnormal Vaginal Bleeding and Women Wellness & Surgery Center :: Focus of Care Perimenopause and Menopause. Changes may occur with the menstrual cycle, Cyclic progesterone can help with bleeding. Flow can also be decreased with a UpToDate Patient information: Abnormal uterine bleeding Premenopausal women Á” Many different conditions can cause abnormal bleeding in women between adolescence and menopause. Abrupt changes in hormone levels at prolonged menstral bleeding perimenopause >> Medical Questions abnormal menstral bleeding · long menstral period excessive bleeding · pre and post menstral Are symptoms in perimenopause the same as in menopause? á» Menorrhagia or perimenopause - Menopause Help natural help with menopause, help for hot flashes and menopause This abnormal bleeding is sometimes caused as an outcome of one ovulation that has not IngentaConnect Abnormal Uterine Bleeding on Hormone Replacement Methods: Between May 1991 and May 1993, women presenting with abnormal withdrawal bleeding on HRT (n = 106), menstrual problems in pre-menopause (n = 92), Premenopause: how to tell if its happening to you - Menstruation Some women might have abnormal bleeding. Add 'Premenopause: how to tell if it's happening to you' to Windows live · Add 'Premenopause: how to tell if Welcome to gulfMD.com - The world of Health, Progress and Hope Abnormal bleeding during perimenopause, is this normal? It is the time leading up to menopause (when you have not had your period for twelve months). Premature Menopause Symptoms and Premature Menopause Weight Gain First, recognize there are three stages of menopause - premenopause, perimenopause and Tubal ligation may cause an increased abnormal bleeding, Medical Management of Menopause and PreMenopause:Their Another chapter reviews some caveats on abnormal uterine bleeding in the of the menstrual cycle, premenopause, menopause, and the climacteric. Re: Abnormal bleeding during peri-menopause - Menopause - Women's Abnormal bleeding during peri-menopause. Last post 12-28-2007, 3:46 PM by Digby. Abnormal bleeding during peri-menopause. 09-03-2007, 12:12 AM Uterine bleeding - bloods say not perimenopause - Menopause - MedHelp Machelle Seibel, MD - Women's Health, Menopause, ReproductiveMedicine There are many causes for abnormal bleedingBleeding · Bleeding between periods The menopause Heavy menstrual bleeding is the most common reason for having a hysterectomy. . Women in the pre-menopause who take HRT often get breast pain and benign What Is Herbal Medicine? Premenopause/Menopause Symptoms. FLOODING (HEAVY BLEEDING). Heavy bleeding is common in premenopausal women as a response to changing hormonal levels, Sign and Symptom of Perimenopause - Perimenopause: Are You in its Perimenopause, women, menopause, anovulatory, hormones, ovaries, estrogen, progesterone, Abnormal bleeding may be the result of hormonal fluctuations. Menorrhagia: Overlooked Causes of Heavy Menstrual Bleeding Effective Solutions for Premenopause, Bleeding Due to Fibroid Tumors, Hormonal Imbalance . abnormal menstrual bleeding, abnormal bleeding after delivery, Menopause Menopause Archives. heavy pre-menopausasl bleeding TESTIMONIAL is there anything that can be done for Really heavy bleeding in premenopause. PREmenopause and Hormonal Balance from 30 to 50 Discover how to balance your hormones naturally during the premenopause years. progestins which can make symptoms such as abnormal bleeding worse). Perimenopause Symptoms - Pycnogenol and Black Cohosh Information The term ÁœpremenopauseÁ« is often used ambiguously to refer to the 1 or 2 years immediately before the .. Other things can cause abnormal bleeding. |
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